When you get a heart attack or stroke, often depriving brain stroke or heart of oxygen and blood, causing severe damage, and lead to cell death. And this increases the risk of damage when the clot is removed and the blood rushes back into the heart and brain. Until now, it was unclear how the blood flow causes such damage.
But in a study published on the sixth of November 2014 in the scientific journal Nature by a team of researchers from the Medical Research Council, the unity of mitochondrial biology, Unit MRC Cancer, and the University of Cambridge, found that the cause of this damage, the accumulation of a chemical called succinate. This article appears naturally in the body, when it is sugar and fat division for the release of the energy stored in food. The study shows that the succinate accumulates abnormally within the User or cells in the body when the blood flow is limited. When blood flow returns, interact large quantity of the succinate with oxygen while blood rushes to the tissues starved for oxygen. This is what causes the release of destructive molecules that interact with the user cells in the body and gets damaged. After months and years for all heart attack, it is possible for this damage that leads to weakening of the heart muscle, making it difficult for the individual process and the completion of the daily duties or daily activities Kalasthmam or climbing stairs.
By measuring the researchers a range of different chemicals in the vital organs before a heart attack and then through a technique called metabolomics, showing an increase of succinate. Researchers have discovered that they can mitigate the damage Lists by giving chemicals called malonate esters, when blood flow is restored, as malonate esters can reduce the accumulation of succinate and reduce the production of destructive molecules arising. These materials are available in fruit strawberries, grapes, apples and other but not the large quantities required to meet this need.
Aucun commentaire:
Enregistrer un commentaire